Everything about Isatin totally explained
| Section2 =
| Section3 =
}}
}}
Isatin or
1H-indole-2,3-dione is an
indole derivative. The compound was first obtained by Erdman and
Laurent in 1841 as a product from the
oxidation of
Indigo dye by
nitric acid and
chromic acids. The compound is found in many plants.
Schiff bases of Isatin are investigated for their pharmaceutical properties .
It was observed that isatin forms a blue dye if it's mixed with
sulfuric acid and crude
benzene. The formation of the blue
indophenin was long believed to be a reaction with benzene.
Victor Meyer was able to isolate the substance resposible for this reaction from benzene. This new heterocyclic compound was
thiophene.
Preparation
Isatin is commercially available. It may be prepared from cyclicizing the condensation product of
chloral hydrate,
aniline and
hydroxylamine in
sulfuric acid:
Isatins can be made from the corresponding indole in good yield by a mix of
InCl3 and
IBX in a
acetonitrile-
water solution at 80 °C.
Further Information
Get more info on 'Isatin'.
|
External Link Exchanges
Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:
<a href="http://isatin.totallyexplained.com">Isatin Totally Explained</a>
Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned. |
